html,body{font-size:16px !important;line-height:18px !important;height:100%;color:#333;padding:0;margin:0}*,html,body{font-family:"Poppins",sans-serif;font-weight:normal;letter-spacing:normal;-webkit-font-smoothing:antialiased;-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box;text-rendering:geometrirecision;-webkit-tap-highlight-color:rgba(0,0,0,0);outline:none !important;letter-spacing:-0.1px;word-wrap:break-word}.row{display:flex;flex-wrap:wrap;margin-left:-10px;margin-right:-10px;padding:0 2px}.col{flex:0 0 auto;width:25%;margin-bottom:20px;padding-left:10px;padding-right:10px}.col .entity-item{height:100%}strong,b{font-family:"Poppins",sans-serif;font-weight:bold}figure{margin:0;padding:0}a{text-decoration:none;color:#174fae}a:hover{text-decoration:underline}pre{padding:5px;margin-top:20px;background:#f3f3f3;border:1px solid #ccc}p{font-size:18px;line-height:24px}.link{cursor:pointer}.nowrap{white-space:nowrap}.overflow-auto{overflow:auto !important;-webkit-overflow-scrolling:touch !important}.h1,.h2,.h3,.h4,.h5,.h6,h1,h2,h3,h4,h5,h6{font-family:"Poppins",sans-serif;font-weight:bold}.multiple:after{content:',';margin-right:4px}.multiple:last-child:after{content:'';margin-right:0}.icon-home{display:flex;justify-content:center;align-items:center}.icon-home svg{fill:#fff;width:15px;height:15px}.icon svg{fill:#fff;width:35px;height:35px}.m-0{margin:0 !important}.p-0{padding:0 !important}.mt-0{margin-top:0 !important}.mb-0{margin-bottom:0 !important}.mb-2{margin-bottom:10px !important}.me-1{margin-right:5px !important}.me-2{margin-right:10px !important}.mb-4{margin-bottom:20px !important}.mt-2{margin-top:20px !important}.mt-1{margin-top:10px !important}.opacity-0{opacity:0 !important}hr{border:0;border-top:1px solid #ccc}.hide-scrollbar{overflow-x:scroll;scrollbar-width:none}.hide-scrollbar::-webkit-scrollbar{display:none}.d-none{display:none !important}.btn{display:inline-block;font-weight:400;line-height:1.5;color:#212529;text-align:center;text-decoration:none;vertical-align:middle;cursor:pointer;-webkit--select:none;-moz--select:none;-select:none;background-color:transparent;border:1px solid transparent;padding:.375rem .75rem;font-size:1rem;border-radius:.25rem;transition:color .15s ease-in-out,background-color .15s ease-in-out,border-color .15s ease-in-out,box-shadow .15s ease-in-out}.btn:hover{text-decoration:none}.btn-link{font-weight:400;color:#0d6efd;text-decoration:none}.btn-group-sm>.btn,.btn-sm{padding:.25rem .5rem;font-size:.875rem;border-radius:.2rem}.btn-outline-dark{color:#212529;border-color:#212529}.btn-outline-dark a{color:#212529}.btn-outline-dark:hover{color:#fff;background-color:#212529;border-color:#212529}.btn-outline-dark:hover a{color:#fff;text-decoration:none}.btn-outline-light{color:#f8f9fa;border-color:#f8f9fa}.btn-outline-light:hover{color:#000;background-color:#f8f9fa;border-color:#f8f9fa}.btn-secondary{color:#fff;background-color:#6c757d;border-color:#6c757d}.btn-dark{color:#fff;background-color:#001c4c;border-color:#001c4c}.btn-danger{color:#fff;background-color:#dc3545;border-color:#dc3545}.btn-light{color:#000;background-color:#f8f9fa;border-color:#f8f9fa}.btn-rounded{border-radius:50px}.btn-dark:hover{color:#ccc}.btn-outline-dark{color:#212529;border-color:#212529}.btn-outline-dark:hover{color:#fff;background-color:#212529;border-color:#212529}.btn-movie{font-size:25px;line-height:25px;padding:0;border-radius:50% !important;width:60px;height:60px;margin:0 15px 0 0;display:flex;justify-content:center;align-items:center}.btn-movie svg{width:30px;height:30px}.btn-icon{line-height:0}.btn-icon svg{fill:#fff;width:1.1em;height:1.1em}.btn-movie:hover svg{fill:#fff}.breadcrumb{font-size:16px;line-height:30px}.breadcrumb{display:flex;flex-wrap:wrap;padding:0;margin-bottom:1rem;list-style:none}.breadcrumb-item+.breadcrumb-item{padding-left:.5rem}.breadcrumb-item+.breadcrumb-item::before{float:left;padding-right:.5rem;color:#6c757d;content:"/";font-size:12px}.sidebar{display:flex;justify-content:space-between;height:100%;flex-direction:column}.sticky-box{height:100%;width:100%;margin-bottom:20px;padding:0}.banner{position:sticky;top:10px;margin-bottom:20px;margin-left:auto;margin-right:auto}.banner ins{position:sticky;top:10px;text-decoration:none;display:block;overflow:hidden !important}.banner ins:after{content:'PUBLICIDAD';background:#f5f5f5;width:100%;display:block;text-align:center;font-size:12px;line-height:12px;padding:4px 0}.bottom-ad-module{display:none}.roba-mobile{display:none}.roba-mobile,.roba-desktop{min-height:600px}.roba-desktop{display:flex;justify-content:start;align-items:end;flex-direction:column;width:320px;max-width:320px}.board-article-outbrain{margin-bottom:40px}.input-group{position:relative;display:flex;flex-wrap:wrap;align-items:stretch;width:100%}.input-group>.form-control,.input-group>.form-select{position:relative;flex:1 1 auto;width:1%;min-width:0}.input-group:not(.has-validation)>.dropdown-toggle:nth-last-child(n+3),.input-group:not(.has-validation)>:not(:last-child):not(.dropdown-toggle):not(.dropdown-menu){border-top-right-radius:0;border-bottom-right-radius:0}.input-group>:not(:first-child):not(.dropdown-menu):not(.valid-tooltip):not(.valid-):not(.invalid-tooltip):not(.invalid-){margin-left:-1px;border-top-left-radius:0;border-bottom-left-radius:0}.form-control{display:block;width:100%;padding:.375rem .75rem;font-size:1rem;font-weight:400;line-height:1.5;color:#212529;background-color:#fff;background-clip:padding-box;border:1px solid #ced4da;-webkit-appearance:none;-moz-appearance:none;appearance:none;border-radius:.25rem;transition:border-color .15s ease-in-out,box-shadow .15s ease-in-out}.form-control-sm{min-height:calc(1.5em+.5rem+2px);padding:.25rem .5rem;font-size:.875rem;border-radius:.2rem}.container{width:1140px;margin-left:auto;margin-right:auto}.top{margin-bottom:20px}.topbar-container{width:100%;background-color:#001c4c}.topbar{position:relative;display:flex;justify-content:center;padding:10px 0;z-index:2}.header-section{border-top:1px solid #fff;background-color:#eaede2;padding:10px 0;text-align:center}.header-section .header-section-title,.header-section .header-section-title a{font-family:"Poppins",sans-serif;font-weight:700;font-size:26px;line-height:26px;margin:0;padding:0;color:#001c4c}.menu-container{width:100%}.menu{position:relative;display:flex;justify-content:center;border-bottom:1px solid #ffffff59;padding:5px 0;z-index:2;background-color:#f3f3f3}.menu .navbar-nav{display:flex;flex-direction:row;list-style:none;padding:0;margin:0}.menu .navbar-nav .nav-link{display:block;padding:.5rem;text-decoration:none;transition:color .15s ease-in-out,background-color .15s ease-in-out,border-color .15s ease-in-out;color:rgba(0,0,0,.55);font-weight:500;font-size:14px;line-height:14px;text-transform:uppercase}.form-search-container{padding:15px 0;width:auto;background-color:#e9f1f8}.form-search{display:flex;flex-direction:row;justify-content:center;width:1140px;margin-left:auto;margin-right:auto}.form-search form{display:flex;width:50%}.form-search .input-search-autocomplete{background-color:#ffffffa8}.section{width:100%;margin-bottom:40px}.section .section-header{display:flex;align-items:center;justify-content:space-between;border-top:3px solid #001c4c;border-bottom:1px solid #001c4c;margin-bottom:20px}.section .section-header p,.section .section-header h2,.section .section-header h1{font-size:24px;line-height:28px;font-weight:bold;color:#001c4c;font-size:24px;line-height:24px;padding:10px 0;margin:0}.entity-item{display:flex;flex-direction:column;position:relative;width:100%;border-bottom:4px solid #001c4c;background:#f3f3f3;box-shadow:0 0 4px #000;text-align:left;margin-bottom:0}.entity-item .entity-item-details{order:1;padding:10px}.entity-item .entity-title,.entity-item .entity-title a{font-size:18px;line-height:20px;font-family:"Poppins",sans-serif;font-weight:600;color:#333;text-decoration:none;margin-bottom:0;margin-top:0;text-transform:uppercase}.entity-item .entity-title small{font-size:14px;line-height:16px}.entity-item .entity-title a:before{content:"";top:0;left:0;right:0;bottom:0;display:block;margin:0;padding:0;position:absolute;z-index:2}.entity-item .entity-item-image{order:0}.entity-item .figure{position:relative;aspect-ratio:.66666667;display:flex;justify-content:center;align-items:center;background-color:#222;color:#fff;overflow:hidden}.entity-item .figure:after{content:var(--category-var);position:absolute;bottom:5px;right:5px;font-size:14px;line-height:14px;text-align:right;background:#2e579e;color:#fff;font-weight:bold;padding:3px 6px;border-radius:5px}.entity-item .figure .img{position:absolute;top:0;left:0;width:100%;height:100%;object-fit:cover}.footer{background-color:#001c4c;padding:20px 0}.footer .container{display:flex;flex-direction:column;justify-content:center;align-items:center;text-align:center}.footer p{font-size:14px;line-height:1;color:#fff;text-align:center;padding:0 10px}.footer a{color:#ccc}.gallery{display:grid;grid-auto-flow:column;grid-auto-columns:calc(100% / 1.1);gap:10px;overflow-x:scroll;scroll-snap-type:x mandatory;scroll-behavior:smooth}.gallery figure{scroll-snap-align:start;position:relative;aspect-ratio:16 / 9;border-radius:10px;border:1px solid #ccc;display:flex;justify-content:center;align-items:center;background-color:#222;color:#fff;width:100%}.gallery img{position:absolute;top:0;left:0;width:100%;height:100%;object-fit:cover;border-radius:10px}.video-gallery{display:grid;grid-auto-flow:column;grid-auto-columns:calc(100% / 1.1);gap:10px;overflow-x:scroll;scroll-snap-type:x mandatory;scroll-behavior:smooth}.video{scroll-snap-align:start;border-radius:10px;overflow:hidden}.video iframe{width:100%;height:100%;aspect-ratio:16 / 9}.entity-gallery .gallery-row>*{border:1px solid #ffffff00}.entity-gallery .gallery-row{display:grid;grid-auto-flow:column;grid-auto-columns:calc(100% / 4.06);gap:15px;overflow-x:auto;overflow-y:hidden;scroll-snap-type:x mandatory;scroll-behavior:smooth;scroll-padding:0}.entity-gallery .gallery-row-6{grid-auto-columns:calc(100% / 5.9)}.entity-gallery .gallery-column{width:100%;scroll-snap-align:start;object-fit:cover}.entity-gallery .entity-item{display:flex;flex-direction:column;position:relative;margin-bottom:0;height:100%}.carousel-wrapper{position:relative}.carousel-button{position:absolute;top:50%;transform:translateY(-50%);background-color:#00000099;color:white;border:0;padding:10px 10px;cursor:pointer;z-index:10;border-radius:100%;display:flex;justify-content:center;align-items:center}.carousel-button svg{fill:#fff;width:20px;height:20px}.carousel-prev{left:0}.carousel-next{right:0}.accordion{width:100%;border:1px solid #ccc;border-radius:8px}.accordion-item{border-top:1px solid #ccc}.accordion-header{display:flex;justify-content:start;align-items:center;padding:15px;cursor:pointer;font-weight:bold}.accordion-header .badge{background-color:#6c757d;color:#fff;padding:5px 10px;border-radius:4px;font-size:14px}.accordion-checkbox{display:none}.accordion-content{max-height:0;overflow:hidden;transition:max-height .3s ease;padding:0 10px;background-color:#fff}.accordion-checkbox:checked ~ .accordion-content{max-height:500vh;padding:0 10px}.accordion-content .table{width:100%;margin-top:10px;margin-bottom:10px;border-collapse:collapse}.accordion-content .table td{padding:10px;border:1px solid #ddd}.accordion-item:first-of-type{border-top:0}.accordion-header::after{flex-shrink:0;margin-left:auto;content:"+";background-repeat:no-repeat;background-size:1.25rem;transition:transform .2s ease-in-out}.accordion-header h4{font-weight:normal}.accordion-content p{margin-top:0}.no-disponible{text-align:center}@media(max-width:1024px){.container{width:100%}.top{margin-bottom:0}.other-container{width:100%;margin:0;padding-left:15px;padding-right:15px}.col{flex:0 0 auto;width:50%}.menu{display:block}.aside-container{display:none}.form-search{width:100%}.form-search form{display:flex;width:100%;margin:0 15px}.entity-item .entity-title,.entity-item .entity-title a{font-size:16px;line-height:18px}.breadcrumb{margin-bottom:10px;padding-left:15px;padding-right:15px}.gallery{grid-auto-columns:calc(100% / 1.1)}.entity-gallery .gallery-row{grid-auto-columns:calc(100% / 2.3)}.section .section-header p,.section .section-header h2,.section .section-header h1{font-size:20px;line-height:22px}.roba-desktop{display:none}.roba-mobile{position:relative;top:0;margin-bottom:30px;display:flex;justify-content:start;align-items:center;flex-direction:column;width:calc(100vw - 30px);max-width:calc(100vw - 30px)}.roba-mobile ins{position:sticky;top:0}.bottom-ad-module{display:block;position:fixed;bottom:0;left:0;width:100%;margin:0;box-shadow:0 -1px 5px 0 rgba(0,0,0,.2);text-align:center;line-height:0;background:#f5f5f5;z-index:3000004;transition:transform .5s ease,opacity .5s ease}.bottom-ad-module-hidden{transform:translateY(100%);opacity:0}.bottom-ad-module .publi-box__close-btn{display:block;color:#666;background:#f5f5f5;z-index:1000001;font-size:17px;padding:5px;box-shadow:1px -2px 2px 0 rgba(0,0,0,.2);border-top-left-radius:8px;width:28px;height:28px;position:absolute;top:-28px;right:0;cursor:pointer}} .article{width:100%}.movie-header{position:relative;margin-bottom:40px;display:flex;flex-direction:row;align-items:flex-start}.movie-header .figure{position:relative;aspect-ratio:.66666667;display:flex;justify-content:center;align-items:center;background-color:#222;color:#fff;width:250px;flex:0 0 250px;overflow:hidden;margin-right:20px}.movie-header .figure .img{position:absolute;top:0;left:0;width:100%;height:100%;object-fit:cover}.movie-title-container{margin:0 auto;z-index:1;flex:1 1 100%;overflow:hidden}.movie-title-container .title{border-top:4px solid #001c4c;border-bottom:1px solid #ccc;font-weight:bold;font-size:36px;line-height:38px;margin:0;padding:10px 0;margin-bottom:20px;color:#001c4c;text-transform:uppercase}.movie-title-container .author-name{margin-bottom:30px}.movie-title-container .author-name a{font-weight:normal;text-transform:uppercase}.movie-title-container .categories{position:absolute;bottom:0;margin-bottom:0}.movie-title-container .categories-relative{position:relative}.movie-title-container .categories a{margin-bottom:10px;margin-right:5px}.movie-title-container .tagline{margin-bottom:20px}.movie-buttons{display:flex;align-items:center;margin-bottom:20px}.movie-buttons .btn-buy{font-size:20px;line-height:1;font-family:sans-serif;font-weight:normal;text-transform:uppercase;height:60px;justify-content:center;align-items:center;display:flex;padding:0 30px;border-radius:30px}.movie-buttons .discountPercentage{font-size:22px;line-height:22px;font-weight:bold;color:green}.movie-container{display:flex;flex-direction:row}.movie-body{margin:0;width:780px;flex:0 0 780px;overflow:hidden}.aside-container{text-align:right;width:320px;flex:0 0 320px;position:relative;margin-left:40px}.providers{width:100%}.providers .provider-container{margin-bottom:20px}.providers a{margin-right:10px;display:inline-block}.providers a:last-child{margin-right:0}.providers img{width:55px;height:55px;border-radius:5px}.providers .provider-type{display:block;background:#eaede2;padding:5px;margin-bottom:10px;font-weight:bold}.providers .provider-container:last-child{margin-bottom:0}.movie-info .row-info{display:flex;flex-direction:row;margin-top:10px;margin-bottom:10px}.movie-info .col-title{font-size:18px;line-height:24px;width:40%;flex:0 0 40%;display:flex;align-items:center;margin:0;font-weight:normal}.movie-info .col-title .icon{display:flex;margin-right:5px}.movie-info .col-title .icon svg{width:20px;height:20px}.movie-info .col-value{width:60%;flex:0 0 60%}.movie-info .col-value p{padding:0;margin:0}.movie-info .col-value .link{white-space:nowrap;text-overflow:ellipsis;display:block;overflow:hidden}.movie-share{position:fixed;bottom:10px;right:10px;z-index:1000}.movie-share .btn{font-size:25px;line-height:25px;padding:0;border-radius:50% !important;width:60px;height:60px;display:flex;justify-content:center;align-items:center;background:#064cc3}.movie-share .btn svg{width:30px;height:30px;fill:#fff}.circle-wrap{width:60px;height:60px;background:#ccc;border-radius:50%;margin:0 15px 0 0;z-index:1}.circle-wrap .circle{position:relative}.circle-wrap .circle .mask,.circle-wrap .circle .fill{width:60px;height:60px;position:absolute;border-radius:50%}.mask .fill{clip:rect(0,30px,60px,0);background-color:#000}.circle-wrap .circle .mask{clip:rect(0,60px,60px,30px)}.circle-wrap .inside-circle{font-family:sans-serif;width:49px;height:49px;border-radius:50%;background:#064cc3;color:#fff;position:absolute;z-index:100;font-weight:700;font-size:18px;line-height:18px;top:5px;left:5px;display:flex;justify-content:center;align-items:center}@media(max-width:1024px){.movie-body{width:100%;flex:0 0 100%;overflow:unset}.movie-header{flex-direction:column}.movie-header .figure{margin:0;width:100%;flex:0 0 100%;background-color:transparent;aspect-ratio:unset;padding:20px 50px}.movie-header .figure .img{position:relative;height:auto;box-shadow:0 0 10px 0 #333}.movie-title-container{width:100%;margin:0;padding-left:15px;padding-right:15px;text-align:center}.movie-title-container .title{border-top:0;font-size:26px;line-height:30px;margin:0 0 20px 0}.movie-buttons{flex-direction:column;margin-bottom:30px;border-bottom:1px solid #ccc;padding-bottom:20px}.movie-buttons .btn-buy{margin-bottom:10px}.movie-title-container .categories{position:relative}.movie-container{margin:0;padding-left:15px;padding-right:15px}.movie-info .row-info{flex-direction:column}.movie-info .col-title,.movie-info .col-value p,.movie-info .col-value a{margin:0}.movie-info .col-title{width:100%;flex:0 0 100%;font-weight:600}.movie-info .col-value{width:100%;flex:0 0 100%}}
The new, revised and updated 7th edition of Marchs Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions.