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This is an introduction to the quantum theory of light and its broad implications and applications. A significant part of the book covers material with direct relevance to current basic and applied research, such as quantum fluctuations and their role in laser physics and the theory of forces between macroscopic bodies (Casimir effects). The book includes numerous historical sidelights throughout, and approximately seventy exercises. The book provides detailed expositions of the theory with emphasis on general physical principles. Foundational topics in classical and quantum electrodynamics are addressed in the first half of the book, including the semiclassical theory of atom-field interactions, the quantization of the electromagnetic field in dispersive and dissipative media, uncertainty relations, and spontaneous emission. The second half begins with a chapter on the Jaynes-Cummings model, dressed states, and somedistinctly quantum-mechanical features of atom-field interactions, and includes discussion of entanglement, the no-cloning theorem, von Neumann's proof concerning hidden variable theories, Bell's theorem, and tests of Bell inequalities. The last two chapters focus on quantum fluctuations andfluctuation-dissipation relations, beginning with Brownian motion, the Fokker-Planck equation, and classical and quantum Langevin equations. Detailed calculations are presented for the laser linewidth, spontaneous emission noise, photon statistics of linear amplifiers and attenuators, and other phenomena. Van der Waals interactions, Casimir forces, the Lifshitz theory of molecular forces between macroscopic media, and the many-body theory of such forces based on dyadic Green functions areanalyzed from the perspective of Langevin noise, vacuum field fluctuations, and zero-point energy.